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Senior / Staff Machine Learning Research Engineer
Calico
South San Francisco, CAPosted Sep 4, 2026 · 4h ago$220k – $290k
Full-time$220k – $290kSeniorOn-siteBiotech
About this role
Calico is seeking Machine Learning Research Engineers to establish the engineering culture for frontier ML research in drug discovery. You will drive the engineering vision for ML models, from identifying research opportunities to delivering production-grade systems, and optimize model implementation. No biology background is required.
What we are looking for
6- Drive engineering vision for ML models
- Identify high-impact research engineering opportunities
- Deliver production-grade systems
- Translate prototype models into optimized JAX or PyTorch code
- Design and implement evaluation frameworks and benchmarks
- Architect solutions for complex systems challenges
Skills mentioned
4PythonDockerKubernetesMachine Learning
